RightChain Lots minimizes the sum of inventory carrying, changeover, and procurement costs by optimizing production and purchasing lot sizes. The optimization jointly considers setup costs, inventory carrying rates, unit standard costs, demand, and procurement costs. RightChain Lots also considers several lot sizing constraints including production capacity, batch sizes, storage capacity, and handling unit configurations. RightChain Lots has been successfully applied and implemented in aerospace, apparel, automotive, beverage, consumer products, food, healthcare, heavy industry, retail, service parts at BP, Coca-Cola, Colgate, Disney, LiDestri, Hamilton Sundstrand, Home Depot, Honda, Invitrogen, and Procter & Gamble.